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hy 13863 ml141 mce  (MedChemExpress)


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    Structured Review

    MedChemExpress hy 13863 ml141 mce
    Hy 13863 Ml141 Mce, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 21 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy+13863+ml141+mce/Hydroxy-Dynasore/pm41175872-242-24-26
    Average 94 stars, based on 21 article reviews
    hy 13863 ml141 mce - by Bioz Stars, 2026-09
    94/100 stars

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    Gel Extraction:

    Article Title: Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Mouse monoclonal anti-SMPDL3B antibody Santa Cruz Biotechonology Cat# sc-137113; RRID: AB_2193525 Mouse monoclonal anti-SMPDL3B antibody Santa Cruz Biotechonology Cat# sc-376870; RRID: sc-376870 Rabbit polyclonal anti-SMPDL3B antibody PROTEINTECH Group Cat# 16552-1-AP; RRID: AB_2878276 Rabbit monoclonal anti-P-STING Ser 365 (D8F4W) antibody Cell Signaling Technology Cat# 72971; RRID:AB_2799831 Rabbit monoclonal anti-P-TBK1 Ser 172 (D52C2) antibody Cell Signaling Technology Cat# 5483; RRID:AB_10693472 Rabbit polyclonal anti-STING antibody PROTEINTECH Group Cat# 19851-1-AP; RRID: AB_10665370 Rabbit monoclonal anti-STING (D2P2F) antibody Cell Signaling Technology Cat# 13647; RRID: AB_2732796 Rabbit monoclonal anti-TBK1/NAK antibody Cell Signaling Technology Cat# 19851-1-AP; RRID: AB_2255663 Rabbit monoclonal anti-P-IRF3 Ser 396 (4D4G) antibody Cell Signaling Technology Cat# 4947; RRID: AB_823547 Mouse monoclonal anti-IRF3 antibody PROTEINTECH Group Cat# 66670-1-Ig; RRID: AB_2882024 Mouse polyclonal anti-HSV-1 gD antibody Santa Cruz Biotechonology Cat# sc-21719; RRID: AB_627720 Rabbit monoclonal anti-GAPDH (14C10) Cell Signaling Technology Cat# 2118; RRID: AB_561053 Mouse monoclonal anti-GFP antibody ABclonal Cat# AE012; RRID: AB_2770402 Rabbit polyclonal anti-ATPA1 antibody PROTEINTECH Group Cat# 55187-1-AP; RRID: AB_10859621 Rabbit monoclonal anti-LAMP1 antibody Abcam Cat# ab208943; RRID: AB_2923327 Mouse monoclonal anti-Flag antibody PROTEINTECH Group Cat# 66008-4-Ig; RRID: AB_2918475 Bacterial and virus strains E. coli DH5α This paper N/A E. coli BL21-RIL DE3 This paper N/A E. coli DH10Bac This paper N/A Herpes simplex virus 1-GFP (HSV-1-GFP, KOS strain) Daxing Gao, University of Science and Technology of China N/A Vaccinia virus-GFP (VACV-GFP, VR-2035 strain) Haiyan Xie and Lili Huang, Beijing institute of technology N/A Pseudorabies virus (PRV, Bartha strain) Guoyu Yang, Henan Agricultural University N/A Vesicular stomatitis virus-GFP (VSV-GFP) Qiang Ding, Tsinghua University N/A Sendai virus (SeV) Zhengfan Jiang, Peking University N/A Chemicals, peptides, and recombinant proteins Fetal Bovine Serum (FBS) ExCell Cat# FSP500 Dulbecco’s modified Eagle’s medium (DMEM) Gibco Cat# 12800082 RPMI 1640 medium Gibco Cat# 31800105 SIM HF Sino Biological Cat# MHF1 SMM293-TII Sino Biological Cat# M293TII 2’3’-Cgamp This paper N/A 2’3’-c-di-AM(PS)2 (Rp, Rp) MCE Cat# HY-12885A 3’3’-Cgamp This paper N/A GpAp This paper N/A PGpA This paper N/A (Continued on next page) e1 Immunity 58, 1–15.e1–e10, November 11, 2025 .. REAGENT or RESOURCE SOURCE IDENTIFIER LPS Sigma-Aldrich Cat# L4391 IFN-γ This paper N/A IL-1β This paper N/A PI-PLC This paper N/A Hydroxy-Dynasore MCE Cat# HY-13863 ML141 MCE Cat# HY-12755 Bafilomycin A1 MCE Cat# HY-100558 T0901317 MCE Cat# HY-10626 Phosphocholine MCE Cat# HY-B2233B RU.521 MCE Cat# HY-114180 ENPP1-1-IN-14 MCE Cat# HY-147389 IFN-β MCE Cat# HY-P73129 Puromycin Beyotime Biotechnology Cat# ST551-10mg Blasticidin Beyotime Biotechnology Cat# ST018-10mg PFO This paper N/A Polyethyleneimine (PEI) This paper N/A Lipo6000TM Beyotime Biotechnology Cat# C0526-0.5ml Liponanogel (LNG) Rui Kuai, Tsinghua University N/A DMXAA Bide Pharmatech Ltd. Cat# BD126695 LB Broth Premixed Power (Tissue Culture Grade) JSENB Cat# JS0666-50 Critical commercial assays DNeasy Blood & Tissue Kit Qiagen Cat# 69504 DNA Gel Extraction Kit Axygen Cat# 454 Streptavidin Coated Plates, Clear, 96-Well ACROBiosystems Cat# SP-11 2’3’-cGAMP ELISA kit Cayman Cat# 501700 Murine IFNβ ELISA kit Invitrogen Cat# 424001 Mouse IL-6 ELISA kit BOSTER Biological Technology Cat# EK0411 Mouse TNFα ELISA kit BOSTER Biological Technology Cat# EK0527 Mouse IL-1β ELISA kit BOSTER Biological Technology Cat# EK0394 One-Step gDNA Removal and cDNA Synthesis Kit Mei5Bio Cat# MF295-01 TIANamp Genomic DNA Kit TIANGEN Cat# DP304 Experimental models: Cell lines .. RAW264.7 ATCC SC-6003 HEK293T ATCC CRL-3216 Caco-2 ATCC CL-0050 iBMDM cells This paper N/A Vero cells ATCC CCL-81 THP1-Lucia ISG cells InvitroGen thpl-isg RAW-Lucia ISG cells InvitroGen rawl-isg SMPDL3B -/- L929 cells This paper N/A SMPDL3B -/- RAW cells This paper N/A SMPDL3B -/- HEK293T cells This paper N/A SMPDL3B -/- +SMPDL3B WT L929 cells This paper N/A SMPDL3B -/- +SMPDL3B Q346A L929 cells This paper N/A SMPDL3B -/- +SMPDL3B N396A L929 cells This paper N/A (Continued on next page) Immunity 58, 1–15.e1–e10, November 11, 2025 e2

    Enzyme-linked Immunosorbent Assay:

    Article Title: Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Mouse monoclonal anti-SMPDL3B antibody Santa Cruz Biotechonology Cat# sc-137113; RRID: AB_2193525 Mouse monoclonal anti-SMPDL3B antibody Santa Cruz Biotechonology Cat# sc-376870; RRID: sc-376870 Rabbit polyclonal anti-SMPDL3B antibody PROTEINTECH Group Cat# 16552-1-AP; RRID: AB_2878276 Rabbit monoclonal anti-P-STING Ser 365 (D8F4W) antibody Cell Signaling Technology Cat# 72971; RRID:AB_2799831 Rabbit monoclonal anti-P-TBK1 Ser 172 (D52C2) antibody Cell Signaling Technology Cat# 5483; RRID:AB_10693472 Rabbit polyclonal anti-STING antibody PROTEINTECH Group Cat# 19851-1-AP; RRID: AB_10665370 Rabbit monoclonal anti-STING (D2P2F) antibody Cell Signaling Technology Cat# 13647; RRID: AB_2732796 Rabbit monoclonal anti-TBK1/NAK antibody Cell Signaling Technology Cat# 19851-1-AP; RRID: AB_2255663 Rabbit monoclonal anti-P-IRF3 Ser 396 (4D4G) antibody Cell Signaling Technology Cat# 4947; RRID: AB_823547 Mouse monoclonal anti-IRF3 antibody PROTEINTECH Group Cat# 66670-1-Ig; RRID: AB_2882024 Mouse polyclonal anti-HSV-1 gD antibody Santa Cruz Biotechonology Cat# sc-21719; RRID: AB_627720 Rabbit monoclonal anti-GAPDH (14C10) Cell Signaling Technology Cat# 2118; RRID: AB_561053 Mouse monoclonal anti-GFP antibody ABclonal Cat# AE012; RRID: AB_2770402 Rabbit polyclonal anti-ATPA1 antibody PROTEINTECH Group Cat# 55187-1-AP; RRID: AB_10859621 Rabbit monoclonal anti-LAMP1 antibody Abcam Cat# ab208943; RRID: AB_2923327 Mouse monoclonal anti-Flag antibody PROTEINTECH Group Cat# 66008-4-Ig; RRID: AB_2918475 Bacterial and virus strains E. coli DH5α This paper N/A E. coli BL21-RIL DE3 This paper N/A E. coli DH10Bac This paper N/A Herpes simplex virus 1-GFP (HSV-1-GFP, KOS strain) Daxing Gao, University of Science and Technology of China N/A Vaccinia virus-GFP (VACV-GFP, VR-2035 strain) Haiyan Xie and Lili Huang, Beijing institute of technology N/A Pseudorabies virus (PRV, Bartha strain) Guoyu Yang, Henan Agricultural University N/A Vesicular stomatitis virus-GFP (VSV-GFP) Qiang Ding, Tsinghua University N/A Sendai virus (SeV) Zhengfan Jiang, Peking University N/A Chemicals, peptides, and recombinant proteins Fetal Bovine Serum (FBS) ExCell Cat# FSP500 Dulbecco’s modified Eagle’s medium (DMEM) Gibco Cat# 12800082 RPMI 1640 medium Gibco Cat# 31800105 SIM HF Sino Biological Cat# MHF1 SMM293-TII Sino Biological Cat# M293TII 2’3’-Cgamp This paper N/A 2’3’-c-di-AM(PS)2 (Rp, Rp) MCE Cat# HY-12885A 3’3’-Cgamp This paper N/A GpAp This paper N/A PGpA This paper N/A (Continued on next page) e1 Immunity 58, 1–15.e1–e10, November 11, 2025 .. REAGENT or RESOURCE SOURCE IDENTIFIER LPS Sigma-Aldrich Cat# L4391 IFN-γ This paper N/A IL-1β This paper N/A PI-PLC This paper N/A Hydroxy-Dynasore MCE Cat# HY-13863 ML141 MCE Cat# HY-12755 Bafilomycin A1 MCE Cat# HY-100558 T0901317 MCE Cat# HY-10626 Phosphocholine MCE Cat# HY-B2233B RU.521 MCE Cat# HY-114180 ENPP1-1-IN-14 MCE Cat# HY-147389 IFN-β MCE Cat# HY-P73129 Puromycin Beyotime Biotechnology Cat# ST551-10mg Blasticidin Beyotime Biotechnology Cat# ST018-10mg PFO This paper N/A Polyethyleneimine (PEI) This paper N/A Lipo6000TM Beyotime Biotechnology Cat# C0526-0.5ml Liponanogel (LNG) Rui Kuai, Tsinghua University N/A DMXAA Bide Pharmatech Ltd. Cat# BD126695 LB Broth Premixed Power (Tissue Culture Grade) JSENB Cat# JS0666-50 Critical commercial assays DNeasy Blood & Tissue Kit Qiagen Cat# 69504 DNA Gel Extraction Kit Axygen Cat# 454 Streptavidin Coated Plates, Clear, 96-Well ACROBiosystems Cat# SP-11 2’3’-cGAMP ELISA kit Cayman Cat# 501700 Murine IFNβ ELISA kit Invitrogen Cat# 424001 Mouse IL-6 ELISA kit BOSTER Biological Technology Cat# EK0411 Mouse TNFα ELISA kit BOSTER Biological Technology Cat# EK0527 Mouse IL-1β ELISA kit BOSTER Biological Technology Cat# EK0394 One-Step gDNA Removal and cDNA Synthesis Kit Mei5Bio Cat# MF295-01 TIANamp Genomic DNA Kit TIANGEN Cat# DP304 Experimental models: Cell lines .. RAW264.7 ATCC SC-6003 HEK293T ATCC CRL-3216 Caco-2 ATCC CL-0050 iBMDM cells This paper N/A Vero cells ATCC CCL-81 THP1-Lucia ISG cells InvitroGen thpl-isg RAW-Lucia ISG cells InvitroGen rawl-isg SMPDL3B -/- L929 cells This paper N/A SMPDL3B -/- RAW cells This paper N/A SMPDL3B -/- HEK293T cells This paper N/A SMPDL3B -/- +SMPDL3B WT L929 cells This paper N/A SMPDL3B -/- +SMPDL3B Q346A L929 cells This paper N/A SMPDL3B -/- +SMPDL3B N396A L929 cells This paper N/A (Continued on next page) Immunity 58, 1–15.e1–e10, November 11, 2025 e2

    cDNA Synthesis:

    Article Title: Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Mouse monoclonal anti-SMPDL3B antibody Santa Cruz Biotechonology Cat# sc-137113; RRID: AB_2193525 Mouse monoclonal anti-SMPDL3B antibody Santa Cruz Biotechonology Cat# sc-376870; RRID: sc-376870 Rabbit polyclonal anti-SMPDL3B antibody PROTEINTECH Group Cat# 16552-1-AP; RRID: AB_2878276 Rabbit monoclonal anti-P-STING Ser 365 (D8F4W) antibody Cell Signaling Technology Cat# 72971; RRID:AB_2799831 Rabbit monoclonal anti-P-TBK1 Ser 172 (D52C2) antibody Cell Signaling Technology Cat# 5483; RRID:AB_10693472 Rabbit polyclonal anti-STING antibody PROTEINTECH Group Cat# 19851-1-AP; RRID: AB_10665370 Rabbit monoclonal anti-STING (D2P2F) antibody Cell Signaling Technology Cat# 13647; RRID: AB_2732796 Rabbit monoclonal anti-TBK1/NAK antibody Cell Signaling Technology Cat# 19851-1-AP; RRID: AB_2255663 Rabbit monoclonal anti-P-IRF3 Ser 396 (4D4G) antibody Cell Signaling Technology Cat# 4947; RRID: AB_823547 Mouse monoclonal anti-IRF3 antibody PROTEINTECH Group Cat# 66670-1-Ig; RRID: AB_2882024 Mouse polyclonal anti-HSV-1 gD antibody Santa Cruz Biotechonology Cat# sc-21719; RRID: AB_627720 Rabbit monoclonal anti-GAPDH (14C10) Cell Signaling Technology Cat# 2118; RRID: AB_561053 Mouse monoclonal anti-GFP antibody ABclonal Cat# AE012; RRID: AB_2770402 Rabbit polyclonal anti-ATPA1 antibody PROTEINTECH Group Cat# 55187-1-AP; RRID: AB_10859621 Rabbit monoclonal anti-LAMP1 antibody Abcam Cat# ab208943; RRID: AB_2923327 Mouse monoclonal anti-Flag antibody PROTEINTECH Group Cat# 66008-4-Ig; RRID: AB_2918475 Bacterial and virus strains E. coli DH5α This paper N/A E. coli BL21-RIL DE3 This paper N/A E. coli DH10Bac This paper N/A Herpes simplex virus 1-GFP (HSV-1-GFP, KOS strain) Daxing Gao, University of Science and Technology of China N/A Vaccinia virus-GFP (VACV-GFP, VR-2035 strain) Haiyan Xie and Lili Huang, Beijing institute of technology N/A Pseudorabies virus (PRV, Bartha strain) Guoyu Yang, Henan Agricultural University N/A Vesicular stomatitis virus-GFP (VSV-GFP) Qiang Ding, Tsinghua University N/A Sendai virus (SeV) Zhengfan Jiang, Peking University N/A Chemicals, peptides, and recombinant proteins Fetal Bovine Serum (FBS) ExCell Cat# FSP500 Dulbecco’s modified Eagle’s medium (DMEM) Gibco Cat# 12800082 RPMI 1640 medium Gibco Cat# 31800105 SIM HF Sino Biological Cat# MHF1 SMM293-TII Sino Biological Cat# M293TII 2’3’-Cgamp This paper N/A 2’3’-c-di-AM(PS)2 (Rp, Rp) MCE Cat# HY-12885A 3’3’-Cgamp This paper N/A GpAp This paper N/A PGpA This paper N/A (Continued on next page) e1 Immunity 58, 1–15.e1–e10, November 11, 2025 .. REAGENT or RESOURCE SOURCE IDENTIFIER LPS Sigma-Aldrich Cat# L4391 IFN-γ This paper N/A IL-1β This paper N/A PI-PLC This paper N/A Hydroxy-Dynasore MCE Cat# HY-13863 ML141 MCE Cat# HY-12755 Bafilomycin A1 MCE Cat# HY-100558 T0901317 MCE Cat# HY-10626 Phosphocholine MCE Cat# HY-B2233B RU.521 MCE Cat# HY-114180 ENPP1-1-IN-14 MCE Cat# HY-147389 IFN-β MCE Cat# HY-P73129 Puromycin Beyotime Biotechnology Cat# ST551-10mg Blasticidin Beyotime Biotechnology Cat# ST018-10mg PFO This paper N/A Polyethyleneimine (PEI) This paper N/A Lipo6000TM Beyotime Biotechnology Cat# C0526-0.5ml Liponanogel (LNG) Rui Kuai, Tsinghua University N/A DMXAA Bide Pharmatech Ltd. Cat# BD126695 LB Broth Premixed Power (Tissue Culture Grade) JSENB Cat# JS0666-50 Critical commercial assays DNeasy Blood & Tissue Kit Qiagen Cat# 69504 DNA Gel Extraction Kit Axygen Cat# 454 Streptavidin Coated Plates, Clear, 96-Well ACROBiosystems Cat# SP-11 2’3’-cGAMP ELISA kit Cayman Cat# 501700 Murine IFNβ ELISA kit Invitrogen Cat# 424001 Mouse IL-6 ELISA kit BOSTER Biological Technology Cat# EK0411 Mouse TNFα ELISA kit BOSTER Biological Technology Cat# EK0527 Mouse IL-1β ELISA kit BOSTER Biological Technology Cat# EK0394 One-Step gDNA Removal and cDNA Synthesis Kit Mei5Bio Cat# MF295-01 TIANamp Genomic DNA Kit TIANGEN Cat# DP304 Experimental models: Cell lines .. RAW264.7 ATCC SC-6003 HEK293T ATCC CRL-3216 Caco-2 ATCC CL-0050 iBMDM cells This paper N/A Vero cells ATCC CCL-81 THP1-Lucia ISG cells InvitroGen thpl-isg RAW-Lucia ISG cells InvitroGen rawl-isg SMPDL3B -/- L929 cells This paper N/A SMPDL3B -/- RAW cells This paper N/A SMPDL3B -/- HEK293T cells This paper N/A SMPDL3B -/- +SMPDL3B WT L929 cells This paper N/A SMPDL3B -/- +SMPDL3B Q346A L929 cells This paper N/A SMPDL3B -/- +SMPDL3B N396A L929 cells This paper N/A (Continued on next page) Immunity 58, 1–15.e1–e10, November 11, 2025 e2



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    hy 13863 ml141 mce  (MedChemExpress)
    94
    MedChemExpress hy 13863 ml141 mce
    Hy 13863 Ml141 Mce, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy+13863+ml141+mce/Hydroxy-Dynasore/pm41175872-242-24-26
    Average 94 stars, based on 1 article reviews
    hy 13863 ml141 mce - by Bioz Stars, 2026-09
    94/100 stars
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